Specific 5-hydroxylation of piperlongumine by Beauveria bassiana ATCC 7159.
نویسندگان
چکیده
A new hydroxylated derivative was efficiently prepared by transforming the natural anti-cancer product, piperlongumine, with Beauveria bassiana ATCC 7159. Its structure was determined to be 5-hydroxylpiperlongumine on the basis of the spectroscopic data. The absolute configuration at C-5 was established as R by Mosher's method.
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 76 8 شماره
صفحات -
تاریخ انتشار 2012